Biology • Year 12 • Module 7 • Lesson 4

Modes of Transmission

Lock in the three transmission modes, key vocabulary, fomite vs vector distinctions, and epidemic-curve shapes before moving to data analysis.

Build · Vocab & Classification

1. Label the transmission-pathways diagram

The diagram below shows four transmission scenarios for the same pathogen moving between two hosts (or from an environment to a host). Write the correct label into boxes A–H from the lesson's Key Terms and Card 1. 8 marks

Disease transmission pathways — four scenarios
  1. A — transmission mode shown in Panel 1 _______________________
  2. B — droplet size that stays in air briefly and requires close contact _______________________
  3. C — transmission mode shown in Panel 2 _______________________
  4. D — fungal pathogen shown in Panel 2 (named species) _______________________
  5. E — transmission mode shown in Panel 3 _______________________
  6. F — technical term for the contaminated non-living cup/water _______________________
  7. G — transmission mode shown in Panel 4 _______________________
  8. H — word describing how the pathogen relates to a biological vector (e.g. Plasmodium in a mosquito) _______________________
Stuck? Revisit lesson § Key Terms (direct contact, indirect contact, vector, fomite) and Card 1.

2. Term–definition match

The ten definitions below are shuffled. In the right-hand column write the matching term from this list: direct contact, indirect contact, vector, fomite, epidemic curve, point source outbreak, biological vector, mechanical vector, droplet nucleus, vertical transmission. 10 marks

#Definition (shuffled)Matching term
2.1An outbreak caused by a single, common exposure at one point in time, producing a sharp peak in the epidemic curve.
2.2Transmission where a pathogen passes directly from one host to another without an intermediate object or organism.
2.3A non-living contaminated object or surface capable of transmitting a pathogen (e.g. a door handle, shared towel).
2.4A living organism that carries and transmits a pathogen between hosts; usually an arthropod.
2.5A bar graph that plots the number of new disease cases against the date or time of symptom onset.
2.6A type of vector in which the pathogen completes part of its life cycle and multiplies inside the vector organism (e.g. Anopheles mosquito for malaria).
2.7Transmission through a contaminated intermediate — object, food, water, soil, or airborne particles — rather than between hosts directly.
2.8A type of vector that carries the pathogen on its body surface without hosting its development (e.g. a housefly carrying Salmonella).
2.9A tiny airborne respiratory particle (<5 µm) that remains suspended in air for extended periods and can carry TB or measles.
2.10Transmission of a pathogen from a mother to her offspring — during pregnancy, childbirth or breastfeeding (e.g. HIV, rubella).
Stuck? Revisit lesson § Key Terms panel, Card 1, and the misconceptions box.

3. True or false — with correction

For each statement, circle T or F. If the statement is false, write the corrected version on the line below it. 8 marks (1 for T/F, 1 for correction where false)

3.1 Tuberculosis is transmitted by respiratory droplets greater than 5 µm in diameter that fall quickly due to gravity.    T  /  F

3.2 A fomite is a living organism that carries a pathogen between hosts.    T  /  F

3.3 The Anopheles mosquito is a biological vector for malaria because Plasmodium completes part of its life cycle inside the mosquito.    T  /  F

3.4 A propagated epidemic curve showing successive waves indicates a point-source exposure to contaminated food.    T  /  F

Stuck? Revisit lesson § Card 1 (direct vs indirect), Card 3 (epidemic curves), and the misconceptions box.

4. Classify each disease by its primary transmission mode

Complete the table below. For each disease, write the primary transmission mode (direct contact / indirect contact / vector) and name the specific route within that mode. 10 marks (1 per row, all three columns required)

Disease (pathogen)Primary transmission modeSpecific route (e.g. respiratory droplet, contaminated water, mosquito bite)
Cholera (Vibrio cholerae)
HIV
Tuberculosis (Mycobacterium tuberculosis)
Malaria (Plasmodium spp.)
Salmonellosis (Salmonella spp.)
Dengue fever (DENV)
Influenza (Influenza A virus)
Tetanus (Clostridium tetani)
Ross River virus
Scabies (Sarcoptes scabiei)
Stuck? Revisit lesson § Card 1 mode cards and the comparison table in Card 2.

5. Build a concept map — transmission chain

Draw labelled arrows between the six terms below to show how they connect during a waterborne outbreak. Each arrow must carry a linking phrase (e.g. “contaminates”, “is classified as”, “can be broken by”). Aim for at least 6 labelled arrows. 6 marks

Supplied terms: reservoir (contaminated water source) · fomite · indirect contact · pathogen (Vibrio cholerae) · new host · water treatment.

reservoir (contaminated water source)
pathogen (V. cholerae)
fomite
indirect contact
new host
water treatment
Hint: pathogen lives in the reservoir → reservoir contaminates a fomite → fomite-mediated route is classified as indirect contact → indirect contact reaches the new host → water treatment interrupts which link?

6. Complete the paragraph — epidemic curves

Fill each blank with the correct term from the word bank below. Use each term only once. 8 marks

Word bank: point source • epidemic curve • propagated • incubation period • continuous common source • onset • waterborne • person-to-person

An   is a bar graph that plots the number of new cases of a disease on the y-axis against the date or time of symptom   on the x-axis. Epidemiologists use the shape of the curve to identify the probable transmission pattern before laboratory results are available.

A   curve rises sharply to a single tall peak and then falls quickly, with all cases falling within approximately one   of each other. This pattern indicates that all affected individuals shared a single common exposure at one time — for example, a contaminated meal at a school camp.

When contamination persists over days or weeks — such as a   supply — the curve shows a gradual rise to a plateau rather than a peak. This is a   pattern.

A   curve produces successive waves of cases, each separated by roughly one incubation period and typically larger than the previous wave. This pattern indicates   spread — for example, influenza moving through a classroom.

Stuck? Revisit lesson § Card 3 (epidemic curve shapes).
Answers — Do not peek before attempting

Q1 — Labelled diagram (image pending)

A: direct contact (respiratory droplet). B: >5 µm (large droplets). C: direct contact (skin-to-skin). D: Trichophyton (causes tinea). E: indirect contact (waterborne). F: fomite (the contaminated cup/water). G: vector transmission. H: biological (the pathogen develops/multiplies within the vector — distinguishing biological from mechanical).

Q2 — Term–definition matches

2.1 point source outbreak • 2.2 direct contact • 2.3 fomite • 2.4 vector • 2.5 epidemic curve • 2.6 biological vector • 2.7 indirect contact • 2.8 mechanical vector • 2.9 droplet nucleus • 2.10 vertical transmission.

Q3 — True / false with correction

3.1 False. Correction: TB is transmitted by airborne droplet nuclei (<5 µm) that remain suspended in air for extended periods — they are too small to fall quickly under gravity. Large droplets (>5 µm) are associated with influenza and COVID-19, not TB.

3.2 False. Correction: a fomite is a non-living contaminated object or surface (e.g. a door handle, shared towel). A living organism that carries a pathogen is called a vector.

3.3 True. The Anopheles mosquito is correctly described as a biological vector because Plasmodium undergoes sexual reproduction and part of its sporogonic (sexual) life cycle inside the mosquito.

3.4 False. Correction: a propagated curve (successive waves) indicates person-to-person spread, not point-source exposure. A point source is indicated by a single sharp peak (all cases within one incubation period).

Q4 — Disease classification table

Cholera: indirect contact / waterborne. HIV: direct contact / blood, sexual, or vertical. TB: indirect contact / airborne droplet nuclei (<5 µm). Malaria: vector / Anopheles mosquito bite. Salmonellosis: indirect contact / contaminated food (poultry, eggs). Dengue fever: vector / Aedes aegypti mosquito bite. Influenza: direct contact / respiratory droplets (>5 µm, close contact). Tetanus: indirect contact / soil (C. tetani spores enter via wound). Ross River virus: vector / mosquito bite (several Aedes and Culex species). Scabies: direct contact / skin-to-skin contact.

Q5 — Sample concept map (waterborne outbreak)

Acceptable arrows include: pathogen (V. cholerae)lives inreservoir; reservoircontaminates afomite (e.g. a cup of untreated water); fomiteis the intermediate inindirect contact; indirect contactallows pathogen to reachnew host; water treatmentremoves pathogen from thereservoir; water treatmentbreaks the chain ofindirect contact. Award 1 mark per biologically correct labelled arrow, maximum 6.

Q6 — Cloze paragraph (in order of blanks)

epidemic curveonsetpoint sourceincubation periodwaterbornecontinuous common sourcepropagatedperson-to-person.